The Guenther House is a restaurant, museum and store located at 205 E. Guenther Street in the King William neighborhood of the Bexar County city of San Antonio in the U.S. state of Texas. Currently operated by C. H. Guenther and Son. Inc., the home was originally built as a private residence in 1859 by Pioneer Flour Mills founder Carl Hilmar Guenther. It was listed on the National Register of Historic Places listings in Bexar County, Texas on October 11, 1990.